Many who have heard of the cannabinoid Cannabinol (CBN) have a negative impression of the compound, as it is typically believed to be a degraded compound that appears in old, poorly stored cannabis. However, this bleak perspective is not entirely accurate.
Unlike most cannabinoids, CBN rarely results from the decarboxylation of its acid form (CBNA). Most of the CBN found in cannabis is due to the degradation of THC, wherein the THC has oxidized to CBN.
CBN is either non-psychoactive or very mildly psychoactive. It reduces intraocular pressure in the eye (similar to D9THC), so it can be used in the treatment of Glaucoma without the psychoactive effects of THC. CBN is synergistic with THC for treatment purposes. CBN also fights free radicals in the bloodstream, and it performs similarly to THC in pain reduction treatments.
Of all the cannabinoids, CBN appears to be the most sedative. Not only is it sedative, it takes very little to do the job. The consumption of 2.5mg to 5mg of CBN has the same level of sedation as a mild pharmaceutical sedative, with a relaxed body sensation similar to 5mg to 10mg of diazepam. CBN is synergistic with both CBD and D9THC for inducement of sleeping, and when mixed in the correct ratios, CBN becomes an effective sleep aid of 5-6 hours duration.
As we do more research focused on CBN, we will no doubt discover more fascinating properties of this often misunderstood cannabinoid. In the meantime, CBN appears to be a beneficial alternative to THC for treatment, and patients that require low (or no) adverse psychoactive effects.
Download full PDF report — Tangie Cookies Oil
Read more — Indica or Sativa: Here’s How to Know
Lemberger, L., and H. Rowe. “Clinical pharmacology of nabilone, a cannabinol derivative.” Clinical pharmacology and therapeutics 18.06 (1975): 720-726.
Boissier, J. R. “Clinical pharmacological study and eeg changes of delta-9 tetrahydro-cannabinol effects in human volunteers.” Biochemical Pharmacology23 (1974): 751-755.